- 2023 PTN Annual Review is Now Available February 28, 2024
2023 was another busy and exciting year for the Pediatric Trials Network ...
- Dumela Botswana! PTN Research on Breastfeeding Looks at Antiretroviral Medications January 22, 2024
The Pediatric Trials Network (PTN) said “Dumela” (hello in Setswana) to Botswana as it activated a Botswana-based site in January. The site has already enrolled several participants in the Pharmacokinetic and Safety ...
- PTN Research Informs Fluconazole Label Change February 16, 2024
Data from multiple Pediatric Trials Network (PTN) studies contributed to a recent U.S. Food and Drug Administration (FDA) label ...
- PTN Enrolls Participants in Methadone Study for Adults October 24, 2023
The Pediatric Trials Network (PTN) has enrolled the first participants in a study titled Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose Intravenous Methadone in Healthy Adult Volunteers (MTH02).
This study will evaluate how healthy adults process methadone administered through IV. It is ...
FDA Label Changes
Under the Best Pharmaceuticals for Children Act (BPCA), the PTN works to provide the Food and Drug Administration (FDA) with information to inform label changes with the necessary information to prescribe the most appropriate doses of the medications to children. As a result of research conducted through the BPCA program, led by the PTN, the following label changes have been made:
- Acyclovir
- Ampicillin
- Caffeine
- Clindamycin (2)
- Diazepam
- Doxycycline
- Levetiracetam
- Lisinopril
- Lithium
- Lorazepam
- Mercy babyTAPE
- 2D and 3D Mercy TAPE
- Meropenem
- Propylthiouracil
- Pralidoxime
- Rifampin
- Sodium nitroprusside
- Fluconazole
REFLECTIONS ON PEDIATRIC CLINICAL RESEARCH
The Pediatric Trials Network (PTN) partnered with the International Children’s Advisory Network (iCAN) to produce an anthology that highlights iCAN members’ perspectives on the pediatric clinical research process. A formal publication will eventually be produced as a way of engaging families in the clinical research process. Take a look at some of the submissions received thus far.
Results At-A-Glance
The Pediatric Trials Network works to make medication safer and more effective for all children. As part of that work, we share what we learn with all stakeholders through result summaries. We appreciate every family who participates in research and makes this work possible.
Evidence Into Practice
The leader in pediatric research of off-patent drugs
