PTN News

  • 2023 PTN Annual Review is Now Available February 28, 2024
    2023 was another busy and exciting year for the Pediatric Trials Network (PTN). This year, the Network upheld its commitment to improving pediatric care by changing labels, performing research, connecting with partners, and sharing science. The PTN would like to thank its participants, members, and partners for their continued support in making a difference for ...
  • PTN Research Informs Fluconazole Label Change February 16, 2024
    Data from multiple Pediatric Trials Network (PTN) studies contributed to a recent U.S. Food and Drug Administration (FDA) label change for fluconazole. The data that informed the label update, which is extensive, came from the following studies: Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants < 750 Grams Birth Weight Pharmacokinetics of a Fluconazole Loading Dose ...
  • Dumela Botswana! PTN Research on Breastfeeding Looks at Antiretroviral Medications January 22, 2024
    The Pediatric Trials Network (PTN) said “Dumela” (hello in Setswana) to Botswana as it activated a Botswana-based site in January. The site has already enrolled several participants in the Pharmacokinetic and Safety of Antiretroviral and Related Drugs in Lactating Women and Breastmilk Fed Infants (BMS02) study. This study will help answer important questions about breastfeeding ...
  • PTN Enrolls Participants in Methadone Study for Adults October 24, 2023
    The Pediatric Trials Network (PTN) has enrolled the first participants in a study titled Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose Intravenous Methadone in Healthy Adult Volunteers (MTH02). This study will evaluate how healthy adults process methadone administered through IV. It is essential for determining the optimal dose of methadone and to understand variations in ...
  • Investigator Spotlight: Dr. Susan Rahman October 16, 2023
    Q: Could you tell us about yourself (background, areas of interest, expertise, etc.)? A: I’ve been a pediatric researcher and innovator for nearly 30 years overseeing basic, clinical, and translational research programs. I’ve been funded by an array of sponsors (e.g. the National Institutes of Health, World Health Organization, Centers for Diseases Control and Prevention, National ...
  • PTN’S CUDDLE Study Will Assess Additional Drugs September 15, 2023
    Pediatric Trials Network (PTN)’s BMS study (NICHD-2017-BMS01) of Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants (CUDDLE), has added new drugs to the list of drugs being studied; marking a substantial milestone in determining the safety of drugs passed through breastmilk. The study will assess the following additional drugs to determine ...
  • PTN Research Informs Levetiracetam Label Change September 11, 2023
    A pharmacokinetic (PK) study by the Pediatric Trials Network (PTN) has contributed to a recent label change for levetiracetam, an anti-epileptic drug. The U.S. Food and Drug Administration (FDA) updated the dosage information for levetiracetam based on the PTN studies Pharmacokinetics of Anti-epileptic Drugs in Obese Children (AED01) and Pharmacokinetics of Understudied Drugs Administered to ...
  • PTN Team Presents at Annual iCAN Summit July 25, 2023
    Members of the Pediatric Trials Network (PTN) team recently had the opportunity to attend, participate, and present at the 2023 International Children’s Advisory Network (iCAN) Summit in La Jolla, California. Global Trials Associate Director, Phyllis Kennel, and Research Communications and Engagement Specialist, Meagan Daly, presented to a group of young people and industry representatives. The presentation ...
  • PTN Sildenafil Study Opens Final Cohort June 26, 2023
    The Pediatric Trials Network (PTN) has opened the third cohort, or group of study participants, in the second phase of the Safety of Sildenafil in Premature Infants study. This is a major study milestone as it will help determine the safety of a higher dose of sildenafil in premature infants. Each cohort has received a ...
  • PTN Now Provides Methods for Analyzing Drug Concentration June 23, 2023
    Many PTN studies measure the concentration of certain drugs in children’s bodies. The PTN collaborates with several laboratories to develop and validate methods for analyzing biological samples. The PTN is now sharing these methods with the research community. The PTN Methods page contains a list of drugs studied by the PTN along with the type of ...
 
 

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