PTN News

  • StaR Child Summit 2012 March 30, 2012
  • Enrollment grows in the PTN hydroxyurea study March 27, 2012 The PTN’s hydroxyurea (HU) study is kicking into high gear, with sites reportedly expecting an influx of at least 5 newly enrolled patients over the upcoming spring holiday. Hydroxyurea is the only major drug breakthrough for the treatment of sickle cell disease within the past 20 years. Although it is approved by the Food and Drug ...
  • PTN investigator Kelly Wade talks about why research matters and patient safeguards in clinical research March 16, 2012 Why is it important that we do research in infants and children? The only way to safely dose medicine for children is to study the medicine in children. When it comes to how the body handles a medication, we have to remember that children are not small adults and infants are not even small children. Fortunately, ...
  • The PTN lisinopril study to begin enrolling patients in April 2012 March 9, 2012 A study to determine the safety and pharmacokinetics of lisinopril in children and adolescents receiving kidney transplants will begin enrolling participants in April 2012. Lisinopril is approved by the U.S. Food and Drug Administration for the treatment of children aged 6 years and older and adults with high blood pressure, heart failure, and heart attack. High ...
  • First patient enrolled in hydroxyurea study February 13, 2012 Breaking news announcement On January 27, 2012, the first patient was successfully enrolled into the PTN’s hydroxyurea (HU) study. Hydroxyurea is the only major drug breakthrough for the treatment of sickle cell disease within the past 20 years. It is the only drug approved by the FDA to treat adults with sickle cell anemia, and so it ...
  • DCRI researchers complete first drug study for Pediatric Trials Network January 23, 2012 DCRI investigators have completed the study of metronidazole, an anti-microbial agent frequently administered to infants suffering from necrotizing enterocolitis. The Duke Clinical Research Institute has completed its first drug trial conducted for the Pediatric Trials Network (PTN). Late last year (2011), DCRI investigators completed their study of metronidazole, an anti-microbial agent frequently administered to infants suffering from ...
  • 2011 BPCA Priority List of Pediatric Therapeutic Needs released January 19, 2012 The 2011 BPCA Priority List of Pediatric Therapeutic Needs and the 2011 BPCA Priority List of Pediatric Therapeutic Needs under Consideration was released on April 1, 2011. Please refer to the Federal Register Notice for additional details.
  • Putting an end to “ballpark dosing” in children January 6, 2011 Doctors make educated guesses every day. There’s precious little time to decide what treatment to use, much less how often or how much to prescribe, when there are dozens of patients waiting to be seen.That’s why they rely so much on clinical practice guidelines—statements that describe appropriate treatments based on scientific evidence and broad consensus ...
  • New national initiative to rigorously study pediatric dosing safety of prescription medicines September 15, 2010 A groundbreaking effort to reduce the risks and dangers faced everyday by millions of children who are prescribed medications that lack definitive data about pediatric dosing, efficacy and safety was created today through an initiative supported by the National Institutes of Health (NIH), totaling up to $95 million over the next seven years. The initiative, a ...