PTN Investigator Profiles

Adam Frymoyer: PTN Principal Investigator at the University of California–San Francisco Combining a passion for pediatric care with an interest in pharmacology, Adam Frymoyer contributes a multi-dimensional perspective to the Pediatric Trials Network. He’s a pediatrician who enjoys providing care for newborns, both those who are well and those who are sick and in need of special treatment to make the transition home. He’s also a ...

Adriana Tremoulet: PTN Principal Investigator at Rady Children’s Hospital, San Diego Dr. Tremoulet is a pediatric infectious disease specialist who cares for children at Rady Children’s Hospital, San Diego. As part of the PTN, she is the site principal investigator responsible for the enrollment of study-eligible subjects into the POPS/PTN study of drugs used in children as a standard part of care. Her research interests include pediatric ...

Antonio Arrieta: PTN Principal Investigator at Children’s Hospital of Orange County Director of Pediatric Infectious Diseases at Children’s Hospital of Orange County (CHOC), California, Dr. Antonio Arrieta is a board-certified pediatric infectious disease specialist who leads a team of 5 physicians providing inpatient and outpatient consults for the hospital and the community. He also directs the pediatric HIV treatment center. Physicians trained in pediatric infectious disease treat ...

Brenda Poindexter: PTN Principal Investigator at Riley Hospital for Children in Indianapolis Brenda Poindexter is a clinical neonatologist, which means that she specializes in the care, development, and diseases of newborn infants (neonates), both premature and full-term. Working in a neonatal intensive care unit (NICU), she tackles issues related to premature birth, low birth weight, sepsis (infection) and septic shock, birth defects, critical illness, respiratory problems, and ...

Daniel Feig: PTN Principal Investigator at Children’s of Alabama in Birmingham High blood pressure (also known as hypertension) is not often associated with children in everyday conversation, but, as Daniel Feig knows, it’s a problem that’s afflicting more kids every year. In fact, the rate of hypertension in children has almost tripled in the past 30 years. Dr. Feig encounters the reality behind this troubling statistic ...

Debbie Gipson: PTN Principal Investigator at C.S. Mott Children’s Hospital, University of Michigan, Ann Arbor The adage that children should be seen but not heard does not ring true for Debbie Gipson. A pediatric nephrologist at the C.S. Mott Children’s Hospital of the University of Michigan, she has devoted her research career to investigating the health needs and outcomes of children suffering from diseases involving the kidneys. Fittingly, as high ...

Howard Trachtman: PTN Principal Investigator at New York University Langone Medical Center As a pediatric nephrologist, Howard Trachtman treats children with a wide range of kidney problems, from acute kidney disease to chronic kidney failure. The kidneys play a critical role in the body by acting as a filtering system, controlling water levels and eliminating wastes through urine. They also help regulate blood pressure, red blood cell ...

Ian Paul: PTN Principal Investigator at the Penn State Children’s Hospital Ian Paul brings a unique perspective to the PTN. A professor of pediatrics and public health sciences at the Pennsylvania State University College of Medicine and director of research in the Division of General Pediatrics at Penn State Children’s Hospital, he is the only PTN Steering Committee member who works in primary care as a ...

Janice Sullivan: PTN Principal Investigator at the University of Louisville and Kosair Children’s Hospital Dr. Janice Sullivan is a pediatric intensivist in the Kosair Charities Pediatric Clinical Research Unit at the University of Louisville and Kosair Children’s Hospital in Louisville, Kentucky, which means that she specializes in caring for infants, children, and adolescents with serious illnesses or injuries. She’s also a clinical pharmacologist with a focus on pediatrics and ...

Joseph Flynn: PTN Principal Investigator at Seattle Children’s Hospital Dr. Joseph Flynn is a professor of pediatrics and chief of the Division of Nephrology at Seattle Children’s Hospital. His personal vision for clinical research can be summarized quite simply: “For years, I have felt that every patient that we see should be viewed as a potential research subject. We’ll never advance our understanding of ...

Kelli Brown: PTN Study Coordinator at the University of Louisville and Kosair Children’s Hospital When asked about her research staff in the Kosair Charities Pediatric Clinical Research Unit at the University of Louisville and Kosair Children’s Hospital, Dr. Janice Sullivan is quick to recognize Kelli Brown, the primary coordinator for the POPS study at her site. “She is doing a tremendous job!” effuses Dr. Sullivan. A research nurse coordinator for ...

Kelly Wade: PTN Principal Investigator at the Children’s Hospital of Philadelphia Kelly Wade, MD, PhDKelly Wade is committed to improving drug safety for children. A neonatologist for the Children’s Hospital of Philadelphia, she works in the newborn intensive care units at both Children’s Hospital and Pennsylvania Hospital. Every day, she prescribes life-saving medicines to her tiny patients, often assigning doses based on estimates derived from adult dosing guidelines because ...

Matthew Laughon: PTN Principal Investigator at the University of North Carolina–Chapel Hill Matthew Laughon is on a mission to improve children’s health. An associate professor of pediatrics at the University of North Carolina in Chapel Hill, NC, he not only cares for patients in the North Carolina Children’s Hospital Newborn Critical Care Center, but he also serves as a member of the PTN Steering Committee and as ...

Michael O’Shea: PTN Principal Investigator at Wake Forest University Michael O’Shea—vice chair and professor of pediatrics at Wake Forest University Health Sciences in Winston-Salem, NC—provides leadership for PTN studies of clinical devices, such as new monitoring equipment for infants in the neonatal intensive care unit. A graduate of the Schools of Medicine and Public Health at the University of North Carolina in Chapel Hill, ...

Vance Fowler Jr.: PTN Principal Investigator at Duke University Medical Center Dr. Vance Fowler ‘s interest in infectious disease blossomed in the highland rainforests of Tanzania, where he spent a year studying malaria during medical school as a Rotary Scholar. “What a blast,” recalls Fowler. “From plague outbreaks and river blindness to smallpox scars and rabid dog bites, this year was a crash course in infectious ...